Doctors News Hubb
Advertisement Banner
  • Home
  • News
  • Healthcare
  • Public Health
  • Paramedic
  • Nursing
  • Contact Us
No Result
View All Result
  • Home
  • News
  • Healthcare
  • Public Health
  • Paramedic
  • Nursing
  • Contact Us
No Result
View All Result
Doctors News Hubb
No Result
View All Result
Home News

Metformin and Survival in Diabetes-related In-hospital Cardiac Arrest

admin by admin
December 22, 2022
in News


The following is a summary of “Association between metformin and survival outcomes in in-hospital cardiac arrest patients with diabetes” published in the October 2022 issue of Critical Care by Jin, et al.


Metformin’s neuroprotective and cardioprotective properties have been demonstrated in animal models of cardiac arrest and ischemia-reperfusion injury. Therefore, the purpose of this study was to assess whether or not type 2 DM (T2DM) patients who experienced in-hospital cardiac arrest (IHCA) benefited from taking their diabetes medication before and throughout their hospital stay.

Between April 2017 and March 2022, adult IHCA patients with T2DM were included in retrospective observational research. The timing of diabetes medication use within the last 24 hours preceding cardiac arrest was a key variable. To examine the correlation between these factors, a multivariate logistic regression was conducted.

Metformin given within 24 hours before IHCA improved survival to discharge and neurologic prognosis in 377 patients (41.5% vs 11.7%, P<0.001 and 18.9% vs 6.2%, P=0.004, respectively). Survival to discharge and favorable neurologic outcome were independently linked with metformin administration within 24 hours before IHCA (adjusted odds ratio [aOR]: 5.37, 95% CI: 2.13-13.53, P<0.001 and aOR: 3.57, 95% CI: 1.14-11.17, P=0.029). Patients who were given 500-1000 mg of metformin daily had the highest rate of survival to discharge (P<0.001). Patients with type 2 diabetes who experienced IHCA had a higher chance of surviving to discharge if they had been given metformin within the preceding 24 hours.

Source: sciencedirect.com/science/article/abs/pii/S0883944122002003



Source link

Advertisement Banner
Previous Post

Benefits & Risks of Prehospital Drug Assisted Airway Management (DAAM)

Next Post

Netflix for Drugs? – The Health Care Blog

Related Posts

News

Novel Non-Antibody Fusion Protein Effective for Sjögren’s Syndrome

June 7, 2023
News

Examining the Role of Vedolizumab and Ustekinumab in Biologic-Naïve Patients With CD

June 6, 2023
News

Understanding the Progression of Very Early-Onset Inflammatory Bowel Disease: A Clinical Perspective

June 5, 2023
News

ASCO: Phone-Based Coaching Helps Breast Cancer Patients Lose Weight

June 4, 2023
News

Double Dissociation of Orientation & Brightness Judgments: Investigating Visual Crowding Effects

June 3, 2023
News

Strategies for Enhancing Workforce Representation

June 2, 2023
Next Post

Netflix for Drugs? – The Health Care Blog

Recommended

Hospitals that denied emergency abortions broke federal law

1 month ago

How journalists found that some telehealth startups share patient information with social media trackers

2 months ago

Extended Mortality Risks in Children with Inborn Metabolic Errors

3 months ago

With CVS-Signify Health deal closed, Signify CEO looks ahead

2 months ago

What are the Benefits of Using CleanTech® EVO for Hand Hygiene?

3 months ago

© Doctors News Hubb All rights reserved.

Use of these names, logos, and brands does not imply endorsement unless specified. By using this site, you agree to the Privacy Policy and Terms & Conditions.

Navigate Site

  • Home
  • News
  • Healthcare
  • Public Health
  • Paramedic
  • Nursing
  • Contact Us

Newsletter Sign Up.

No Result
View All Result
  • Home
  • News
  • Healthcare
  • Public Health
  • Paramedic
  • Nursing
  • Contact Us

© 2022 Doctors News Hubb All rights reserved.