The following is the summary of “Impact of fluid overload on blood pressure variability in patients on peritoneal dialysis” published in the November 2022 issue of Renal failure by Jin, et al.
Those undergoing CAPD frequently have the issue of fluid overload through continuous ambulatory peritoneal dialysis (CAPD). In these patients, blood pressure has traditionally been used as an indicator of fluid status. Yet, its sensitivity is quite low. The fluid volume measurement in hemodialysis patients can benefit from using blood pressure variability (BPV), which can detect fluctuations in blood pressure earlier and more precisely. Unfortunately, patient-centered studies on chronic obstructive pulmonary disease are scarce.
From January 2018 through December 2020, 175 patients on CAPD were enrolled in this retrospective study, all of whom had their peritoneal dialysis adequacy assessed at their center every 2-3 months. A body composition monitor was used to determine the overhydration (OH) value. The BPV for each patient undergoing peritoneal dialysis was calculated using readings taken at regular intervals over the course of a year. Patients were classified as having normal volume (OH ≤2 L), mild volume overload (OH 2-4 L), or severe volume overload (OH≥4 L). The average blood pressure did not vary significantly (P>0.05) between the groups.
Compared to the other groups, those with severe volume overload had greater systolic and diastolic BPV values (P<0.05). Correlation and regression analyses revealed a positive relationship between volume overload severity and BPV. BPV was also significantly associated with PD volume-related indices such as diabetes mellitus, blood parathyroid hormone levels, Kt/V, and subjective global assessment scores in the volume overloaded group (P<0.05). Taken together, these findings suggested that BPV could be a helpful indicator of fluid status in PD patients.
Source: tandfonline.com/doi/full/10.1080/0886022X.2022.2148535
