Doctors News Hubb
Advertisement Banner
  • Home
  • News
  • Healthcare
  • Public Health
  • Paramedic
  • Nursing
  • Contact Us
No Result
View All Result
  • Home
  • News
  • Healthcare
  • Public Health
  • Paramedic
  • Nursing
  • Contact Us
No Result
View All Result
Doctors News Hubb
No Result
View All Result
Home News

CRP Taken as Part of a Sepsis Workup While in the NICU

admin by admin
February 15, 2023
in News


The following is the summary of “Time from symptom onset may influence C-reactive protein utility in the diagnosis of bacterial infections in the NICU” published in the December 2022 issue of Pediatrics by Borowski, et al.


C-reactive protein (CRP) testing may function better in identifying bacterial infections in the neonatal intensive care unit (NICU) if the time of the test is considered. In this study, researchers looked at how the yield of CRP changed as time progressed from the onset of symptoms. Patients were enrolled if they were being treated in the NICU and had a CRP drawn as part of a sepsis workup. A record was kept of when symptoms started and when blood was taken. According to the standards set forth by the National Healthcare Safety Network (NHSN), patients were divided into two categories: those with and without bacterial infections. 

Receiver-operating characteristic (ROC) curve analysis was used to compare the effectiveness of CRP, CRP velocity, and CRP collected before or after 6 hours from the beginning of symptoms. Bayesian formulas were used to determine test characteristics. A total of 21 (or 16%) of the 129 newborns enrolled in the trial were infected with germs. Area under the receiver operating characteristic curve was 0.75 (95% CI: 0.61-0.89) for a single CRP test and 0.77 (95% CI:0.66-0.88) for CRP velocity when determining the presence of bacterial infection. For CRP tests taken within 6 hours of symptom onset, a cutoff value of 1 mg/dL is recommended, while for those taken less than 6 hours later, a cutoff value of 1.5 mg/dL is recommended. 

The probability ranged from 35% to 38% after using the appropriate cut-off settings, up from 16% before the test. CRP has a low diagnostic accuracy for babies born weighing less than 1000 g. Diagnosing bacterial infections in NICU patients using the appropriate CRP cut-off varies with time from symptom onset. When blood cultures continue to be negative for bacteria and other germs, a “negative” CRP may lend credence to the decision to discontinue empiric antimicrobial treatment.

Source: bmcpediatr.biomedcentral.com/articles/10.1186/s12887-022-03783-4



Source link

Advertisement Banner
Previous Post

Assembling the Right Components for Your Portable Suction Machines

Next Post

All Three Legs of the Obamacare Stool Are Working Well – The Health Care Blog

Related Posts

News

#VisualAbstract: Secukinumab reduces symptoms of moderate-to-severe hidradenitis suppurativa

March 26, 2023
News

Over-the-Scope Clip Beneficial for Nonvariceal Upper GI Bleeding

March 25, 2023
News

Patients with Burns and a Multimodal Pain Management Approach

March 24, 2023
News

Insights from Normalization Process Theory

March 23, 2023
News

Transdermal Testosterone Pretreatment Improves Live Birth Rates in Poor Responders

March 22, 2023
News

Ph-positive Acute Lymphoblastic Leukaemia Treated with Ponatinib and Blinatumomab

March 21, 2023
Next Post

All Three Legs of the Obamacare Stool Are Working Well – The Health Care Blog

Recommended

Commercial Hand Wash Sinks Vs CleanTech®

4 months ago

WinkBed Mattress Review 2022 – The Sleep Doctor

5 months ago

Airway Management and Patient Concerns During Anesthesia

4 months ago

Lifespan names John Fernandez, Mass General Brigham executive, CEO

4 months ago

Insurtechs Oscar, Clover and Bright had a rough 2022

3 months ago

© 2022 Doctors News Hubb All rights reserved.

Use of these names, logos, and brands does not imply endorsement unless specified. By using this site, you agree to the Privacy Policy and Terms & Conditions.

Navigate Site

  • Home
  • News
  • Healthcare
  • Public Health
  • Paramedic
  • Nursing
  • Contact Us

Newsletter Sign Up.

No Result
View All Result
  • Home
  • News
  • Healthcare
  • Public Health
  • Paramedic
  • Nursing
  • Contact Us

© 2022 Doctors News Hubb All rights reserved.