Doctors News Hubb
Advertisement Banner
  • Home
  • News
  • Healthcare
  • Public Health
  • Paramedic
  • Nursing
  • Contact Us
No Result
View All Result
  • Home
  • News
  • Healthcare
  • Public Health
  • Paramedic
  • Nursing
  • Contact Us
No Result
View All Result
Doctors News Hubb
No Result
View All Result
Home News

Salivary Steroid Hormones in ASD Boys

admin by admin
March 6, 2023
in News


The following is a summary of the “Analysis of salivary steroid hormones in boys with autism spectrum disorder,” published in the February 2022 issue of Psychiatry by He, et al.


ASD is a neurodevelopmental condition with high prevalence and a difficult diagnosis. This study examined salivary cortisol, DHEA, and pregnenolone as biomarkers for ASD children.

About 55 boys with ASD comprised the experimental group, and 24 neurotypical boys were the control group. Boys with ASD were assessed using the CBCL, ABC, SRS, and RBS. ABSSCIEX QTRAP® 6500 + LC/MS/MS assessed saliva cortisol, DHEA, and pregnenolone concentrations. SPSS 23.0 analyzed data. 

T-tests were used to compare the 2 normal-distributed groups, whereas Mann–Whitney U tests were used for the other 2. Spearman’s correlation analysis correlated 2 variables. ROC analysis assessed each hormone’s discriminating sensitivity between ASD and normal control groups. Logistic regression models examined DHEA and salivary pregnenolone as ASD biomarkers. ASD and control groups had similar ages and weights. The ASD group had considerably higher ABC, SRS, RBS, and CBCL scale scores. 

The ASD group had higher salivary DHEA and pregnenolone levels than the normal control group, but cortisol levels were similar.  Only pregnenolone correlated with ABC in Spearman’s analysis. Logistic regression showed that salivary pregnenolone predicted ASD independently. Pregnenolone distinguished ASD from normal controls well in ROC analysis. Although cases are confined to this high anticipation, the salivary preoperative biomarker was allowed.

Source: bmcpsychiatry.biomedcentral.com/articles/10.1186/s12888-023-04586-2



Source link

Advertisement Banner
Previous Post

Walgreens won’t sell abortion pill mifepristone in some conservative states

Next Post

Ecology Rescued the AMA and Medical Professionalism Beginning in 1870. Will technology and science rescue the profession once again? – The Health Care Blog

Related Posts

News

#VisualAbstract: Secukinumab reduces symptoms of moderate-to-severe hidradenitis suppurativa

March 26, 2023
News

Over-the-Scope Clip Beneficial for Nonvariceal Upper GI Bleeding

March 25, 2023
News

Patients with Burns and a Multimodal Pain Management Approach

March 24, 2023
News

Insights from Normalization Process Theory

March 23, 2023
News

Transdermal Testosterone Pretreatment Improves Live Birth Rates in Poor Responders

March 22, 2023
News

Ph-positive Acute Lymphoblastic Leukaemia Treated with Ponatinib and Blinatumomab

March 21, 2023
Next Post

Ecology Rescued the AMA and Medical Professionalism Beginning in 1870. Will technology and science rescue the profession once again? – The Health Care Blog

Recommended

THCB Gang Episode 116, Thursday February 16 – The Health Care Blog

1 month ago

The Benefits of Keeping a Sleep Diary – The Sleep Doctor

5 months ago

House investigating PBMs Caremark, Express Scripts, OptumRx

3 weeks ago

Our Top 5 Airway Management Blogs of 2022

3 months ago

How to avoid onerous freelance contracts

5 months ago

© 2022 Doctors News Hubb All rights reserved.

Use of these names, logos, and brands does not imply endorsement unless specified. By using this site, you agree to the Privacy Policy and Terms & Conditions.

Navigate Site

  • Home
  • News
  • Healthcare
  • Public Health
  • Paramedic
  • Nursing
  • Contact Us

Newsletter Sign Up.

No Result
View All Result
  • Home
  • News
  • Healthcare
  • Public Health
  • Paramedic
  • Nursing
  • Contact Us

© 2022 Doctors News Hubb All rights reserved.